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Xylazine is known to inhibit norepinephrine release and lipolysis, with dose-dependent effects on epinephrine levels. It also reduces the minimum alveolar concentration (MAC) in horses in a dose- and time-dependent manner. In veterinary use, Xylazine may cause a range of effects including variable analgesia, sedation, ataxia, and cardiovascular and respiratory depression in standing mares. It also increases blood glucose concentration in horses.
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